The ribonuclease activity of Csm6 is required for anti-plasmid immunity by Type III-A CRISPR-Cas systems

CRISPR-Cas systems provide prokaryotes with RNA-based adaptive immunity against viruses and plasmids. A unique feature of Type III CRISPR-Cas systems is that they selectively target transcriptionally-active invader DNA, and can cleave both the expressed RNA transcripts and source DNA. The Type III-A...

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Bibliografiske detaljer
Udgivet i:RNA Biol
Main Authors: Foster, Kawanda, Kalter, Joshua, Woodside, Walter, Terns, Rebecca M., Terns, Michael P.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546353/
https://ncbi.nlm.nih.gov/pubmed/29995577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1493334
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