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Regulation of endothelial barrier integrity by redox-dependent nitric oxide signaling: Implication in traumatic and inflammatory brain injuries

Nitric oxide (NO) synthesized by eNOS plays a key role in regulation of endothelial barrier integrity but underlying cell signaling pathway is not fully understood at present. Here, we report opposing roles of two different redox-dependent NO metabolites; peroxynitrite (ONOO(−)) vs. S-nitrosoglutath...

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Detalhes bibliográficos
Publicado no:Nitric Oxide
Main Authors: Choi, Seungho, Saxena, Nishant, Dhammu, Tajinder, Khan, Mushfiquddin, Singh, Avtar K., Singh, Inderjit, Won, Jeseong
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546177/
https://ncbi.nlm.nih.gov/pubmed/30590116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2018.12.007
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