A dual controllability analysis of influenza virus-host protein-protein interaction networks for antiviral drug target discovery

BACKGROUND: Host factors of influenza virus replication are often found in key topological positions within protein-protein interaction networks. This work explores how protein states can be manipulated through controllability analysis: the determination of the minimum manipulation needed to drive t...

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Detaylı Bibliyografya
Yayımlandı:BMC Bioinformatics
Asıl Yazarlar: Ackerman, Emily E., Alcorn, John F., Hase, Takeshi, Shoemaker, Jason E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545738/
https://ncbi.nlm.nih.gov/pubmed/31159726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2917-z
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