Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer

Heterochromatic repetitive satellite RNAs are extensively transcribed in a variety of human cancers, including BRCA1 mutant breast cancer. Aberrant expression of satellite RNAs in cultured cells induces the DNA damage response, activates cell cycle checkpoints, and causes defects in chromosome segre...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Zhu, Quan, Hoong, Nien, Aslanian, Aaron, Hara, Toshiro, Benner, Christopher, Heinz, Sven, Miga, Karen H., Ke, Eugene, Verma, Sachin, Soroczynski, Jan, Yates, John R., Hunter, Tony, Verma, Inder M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545586/
https://ncbi.nlm.nih.gov/pubmed/29861157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.04.023
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