Effects of Statins on Multispecies Oral Biofilm Identify Simvastatin as A Drug Candidate Targeting Porphyromonas Gingivalis

BACKGROUND: Statins effectively reduce risk of cardiovascular-related morbidity and mortality in patients with hyperlipidemia, hypertension or type-II diabetes. In addition to lowering cholesterol levels, several studies have attributed statins with immunomodulatory and bactericidal properties. Ther...

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Pubblicato in:J Periodontol
Autori principali: Kamińska, Marta, Aliko, Ardita, Hellvard, Annelie, Bielecka, Ewa, Binder, Veronika, Marczyk, Agata, Potempa, Jan, Delaleu, Nicolas, Kantyka, Tomasz, Mydel, Piotr
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545270/
https://ncbi.nlm.nih.gov/pubmed/30506795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JPER.18-0179
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