Tumor Heterogeneity Correlates with Less Immune Response and Worse Survival in Breast Cancer Patients: Tumor heterogeneity correlates with less immune response in breast cancer

BACKGROUND: Intra-tumor heterogeneity implies that sub-populations of cancer cells that differ in genetic, phenotypic, or behavioral characteristics coexist in a single tumor (1,2). Tumor heterogeneity drives progression, metastasis and treatment resistance, but its relationship with tumor infiltrat...

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Vydáno v:Ann Surg Oncol
Hlavní autoři: McDonald, Kerry-Ann, Kawaguchi, Tsutomu, Qi, Qianya, Peng, Xuan, Asaoka, Mariko, Young, Jessica, Opyrchal, Mateusz, Yan, Li, Patnaik, Santosh, Otsuji, Eigo, Takabe, Kazuaki
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545241/
https://ncbi.nlm.nih.gov/pubmed/30963401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-019-07338-3
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