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Older paternal ages and grandpaternal ages at conception predict longer telomeres in human descendants

Telomere length (TL) declines with age in most human tissues, and shorter TL appears to accelerate senescence. By contrast, men's sperm TL is positively correlated with age. Correspondingly, in humans, older paternal age at conception (PAC) predicts longer offspring TL. We have hypothesized tha...

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Detalhes bibliográficos
Publicado no:Proc Biol Sci
Main Authors: Eisenberg, Dan T. A., Lee, Nanette R., Rej, Peter H., Hayes, M. Geoffrey, Kuzawa, Christopher W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545073/
https://ncbi.nlm.nih.gov/pubmed/31138065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2019.0800
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