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Older paternal ages and grandpaternal ages at conception predict longer telomeres in human descendants

Telomere length (TL) declines with age in most human tissues, and shorter TL appears to accelerate senescence. By contrast, men's sperm TL is positively correlated with age. Correspondingly, in humans, older paternal age at conception (PAC) predicts longer offspring TL. We have hypothesized tha...

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Publicat a:Proc Biol Sci
Autors principals: Eisenberg, Dan T. A., Lee, Nanette R., Rej, Peter H., Hayes, M. Geoffrey, Kuzawa, Christopher W.
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545073/
https://ncbi.nlm.nih.gov/pubmed/31138065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2019.0800
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