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Single-cell RNA sequencing reveals the impact of chromosomal instability on glioblastoma cancer stem cells
BACKGROUND: Intra-tumor heterogeneity stems from genetic, epigenetic, functional, and environmental differences among tumor cells. A major source of genetic heterogeneity comes from DNA sequence differences and/or whole chromosome and focal copy number variations (CNVs). Whole chromosome CNVs are ca...
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| Publicado no: | BMC Med Genomics |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6545015/ https://ncbi.nlm.nih.gov/pubmed/31151460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-019-0532-5 |
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