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Widespread selection for extremely high and low levels of secondary structure in coding sequences across all domains of life

Codon composition, GC content and local RNA secondary structures can have a profound effect on gene expression, and mutations affecting these parameters, even though they do not alter the protein sequence, are not neutral in terms of selection. Although evidence exists that, in some cases, selection...

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Detalhes bibliográficos
Publicado no:Open Biol
Main Authors: Gebert, Daniel, Jehn, Julia, Rosenkranz, David
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544989/
https://ncbi.nlm.nih.gov/pubmed/31138098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.190020
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