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Widespread selection for extremely high and low levels of secondary structure in coding sequences across all domains of life

Codon composition, GC content and local RNA secondary structures can have a profound effect on gene expression, and mutations affecting these parameters, even though they do not alter the protein sequence, are not neutral in terms of selection. Although evidence exists that, in some cases, selection...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Open Biol
Hauptverfasser: Gebert, Daniel, Jehn, Julia, Rosenkranz, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Royal Society 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544989/
https://ncbi.nlm.nih.gov/pubmed/31138098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.190020
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