Reversible Gene Expression Control in Yersinia pestis by Using an Optimized CRISPR Interference System

Many genes in the bacterial pathogen Yersinia pestis, the causative agent of three plague pandemics, remain uncharacterized, greatly hampering the development of measures for plague prevention and control. Clustered regularly interspaced short palindromic repeat interference (CRISPRi) has been shown...

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Udgivet i:Appl Environ Microbiol
Main Authors: Wang, Tong, Wang, Min, Zhang, Qingwen, Cao, Shiyang, Li, Xiang, Qi, Zhizhen, Tan, Yafang, You, Yang, Bi, Yujing, Song, Yajun, Yang, Ruifu, Du, Zongmin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Genetics and Molecular Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544824/
https://ncbi.nlm.nih.gov/pubmed/30979834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00097-19
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