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Reversible Gene Expression Control in Yersinia pestis by Using an Optimized CRISPR Interference System

Many genes in the bacterial pathogen Yersinia pestis, the causative agent of three plague pandemics, remain uncharacterized, greatly hampering the development of measures for plague prevention and control. Clustered regularly interspaced short palindromic repeat interference (CRISPRi) has been shown...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Wang, Tong, Wang, Min, Zhang, Qingwen, Cao, Shiyang, Li, Xiang, Qi, Zhizhen, Tan, Yafang, You, Yang, Bi, Yujing, Song, Yajun, Yang, Ruifu, Du, Zongmin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544824/
https://ncbi.nlm.nih.gov/pubmed/30979834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00097-19
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