Strictinin, a novel ROR1-inhibitor, represses triple negative breast cancer survival and migration via modulation of PI3K/AKT/GSK3ß activity

Triple Negative Breast Cancer (TNBC), the most aggressive subtype of breast cancer, is characterized by the absence of hormone receptors usually targeted by hormone therapies like Tamoxifen. Because therapy success and survival rates for TNBC lag far behind other breast cancer subtypes, there is sig...

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Foilsithe in:PLoS One
Main Authors: Fultang, Norman, Illendula, Abhinav, Chen, Brian, Wu, Chun, Jonnalagadda, Subash, Baird, Nathan, Klase, Zachary, Peethambaran, Bela
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2019
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544296/
https://ncbi.nlm.nih.gov/pubmed/31150511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217789
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