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Strictinin, a novel ROR1-inhibitor, represses triple negative breast cancer survival and migration via modulation of PI3K/AKT/GSK3ß activity

Triple Negative Breast Cancer (TNBC), the most aggressive subtype of breast cancer, is characterized by the absence of hormone receptors usually targeted by hormone therapies like Tamoxifen. Because therapy success and survival rates for TNBC lag far behind other breast cancer subtypes, there is sig...

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Vydáno v:PLoS One
Hlavní autoři: Fultang, Norman, Illendula, Abhinav, Chen, Brian, Wu, Chun, Jonnalagadda, Subash, Baird, Nathan, Klase, Zachary, Peethambaran, Bela
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544296/
https://ncbi.nlm.nih.gov/pubmed/31150511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217789
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