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Ligand-Efficient Inhibitors of Trichomonas vaginalis Adenosine/ Guanosine Preferring Nucleoside Ribohydrolase

Trichomoniasis is caused by the parasitic protozoan Trichomonas vaginalis and is the most prevalent, nonviral sexually transmitted disease. The parasite has shown increasing resistance to the current 5-nitroimidazole therapies indicating the need for new therapies with different mechanisms. T. vagin...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Muellers, Samantha N., Gonzalez, Juliana A., Kaur, Abinash, Sapojnikov, Vital, Benzie, Annie Laurie, Brown, Dean G., Parkin, David W., Stockman, Brian J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544043/
https://ncbi.nlm.nih.gov/pubmed/30701958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.8b00346
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