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Anomalies in Dopamine Transporter Expression and Primary Cilium Distribution in the Dorsal Striatum of a Mouse Model of Niemann-Pick C1 Disease

The Niemann-Pick type C1 (NPC1) is a rare genetic disease characterized by the accumulation of endocytosed cholesterol and other lipids in the endosome/lysosome compartments. In the brain, the accumulation/mislocalization of unesterified cholesterol, gangliosides and sphingolipids is responsible for...

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Veröffentlicht in:Front Cell Neurosci
Hauptverfasser: Lucarelli, Micaela, Di Pietro, Chiara, La Sala, Gina, Fiorenza, Maria Teresa, Marazziti, Daniela, Canterini, Sonia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544041/
https://ncbi.nlm.nih.gov/pubmed/31178699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00226
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