Transplantation of CRISPRa system engineered IL10-overexpressing bone marrow-derived mesenchymal stem cells for the treatment of myocardial infarction in diabetic mice

BACKGROUND: Myocardial infarction (MI) is a common cause of mortality in people. Mesenchymal stem cell (MSC) has been shown to exert therapeutic potential to treat myocardial infarction (MI). However, in patients with diabetes, the diabetic environment affected MSCs activity and could impair the eff...

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Dades bibliogràfiques
Publicat a:J Biol Eng
Autors principals: Meng, Xin, Zheng, Minjuan, Yu, Ming, Bai, Wei, Zuo, Lei, Bu, Xin, Liu, Yi, Xia, Linying, Hu, Jing, Liu, Liwen, Li, Jianping
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6543626/
https://ncbi.nlm.nih.gov/pubmed/31164920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-019-0163-6
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