Transplantation of CRISPRa system engineered IL10-overexpressing bone marrow-derived mesenchymal stem cells for the treatment of myocardial infarction in diabetic mice

BACKGROUND: Myocardial infarction (MI) is a common cause of mortality in people. Mesenchymal stem cell (MSC) has been shown to exert therapeutic potential to treat myocardial infarction (MI). However, in patients with diabetes, the diabetic environment affected MSCs activity and could impair the eff...

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Detalhes bibliográficos
Publicado no:J Biol Eng
Main Authors: Meng, Xin, Zheng, Minjuan, Yu, Ming, Bai, Wei, Zuo, Lei, Bu, Xin, Liu, Yi, Xia, Linying, Hu, Jing, Liu, Liwen, Li, Jianping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6543626/
https://ncbi.nlm.nih.gov/pubmed/31164920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-019-0163-6
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