Conditioned Aversion and Neuroplasticity Induced by a Superagonist of Extrasynaptic GABA(A) Receptors: Correlation With Activation of the Oval BNST Neurons and CRF Mechanisms

THIP (gaboxadol), a superagonist of the δ subunit-containing extrasynaptic GABA(A) receptors, produces persistent neuroplasticity in dopamine (DA) neurons of the ventral tegmental area (VTA), similarly to rewarding drugs of abuse. However, unlike them THIP lacks abuse potential and induces condition...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: de Miguel, Elena, Vekovischeva, Olga, Elsilä, Lauri V., Panhelainen, Anne, Kankuri, Esko, Aitta-aho, Teemu, Korpi, Esa R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6543524/
https://ncbi.nlm.nih.gov/pubmed/31178693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00130
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