Conditioned Aversion and Neuroplasticity Induced by a Superagonist of Extrasynaptic GABA(A) Receptors: Correlation With Activation of the Oval BNST Neurons and CRF Mechanisms

THIP (gaboxadol), a superagonist of the δ subunit-containing extrasynaptic GABA(A) receptors, produces persistent neuroplasticity in dopamine (DA) neurons of the ventral tegmental area (VTA), similarly to rewarding drugs of abuse. However, unlike them THIP lacks abuse potential and induces condition...

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Dades bibliogràfiques
Publicat a:Front Mol Neurosci
Autors principals: de Miguel, Elena, Vekovischeva, Olga, Elsilä, Lauri V., Panhelainen, Anne, Kankuri, Esko, Aitta-aho, Teemu, Korpi, Esa R.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6543524/
https://ncbi.nlm.nih.gov/pubmed/31178693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00130
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