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Structural and biochemical characterization of Rv0187, an O-methyltransferase from Mycobacterium tuberculosis

Catechol O-methyltransferase (COMT) is widely distributed in nature and installs a methyl group onto one of the vicinal hydroxyl groups of a catechol derivative. Enzymes belonging to this family require two cofactors for methyl transfer: S-adenosyl-l-methionine as a methyl donor and a divalent metal...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Lee, Sanghyun, Kang, Jihoon, Kim, Jungwook
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6543040/
https://ncbi.nlm.nih.gov/pubmed/31147608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44592-7
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