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Biochemical and Structural Studies of the Mycobacterium tuberculosis O(6)-Methylguanine Methyltransferase and Mutated Variants

Mycobacterium tuberculosis displays remarkable genetic stability despite continuous exposure to the hostile environment represented by the host's infected macrophages. Similarly to other organisms, M. tuberculosis possesses multiple systems to counteract the harmful potential of DNA alkylation....

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Detalhes bibliográficos
Main Authors: Miggiano, Riccardo, Casazza, Valentina, Garavaglia, Silvia, Ciaramella, Maria, Perugino, Giuseppe, Rizzi, Menico, Rossi, Franca
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697256/
https://ncbi.nlm.nih.gov/pubmed/23564173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.02298-12
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