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Purified human anti-Tn and anti-T antibodies specifically recognize carcinoma tissues

Described in several epithelial cancer cells, Tn- (GalNAcα1-O-Ser/Thr) and T- (Galβ3GalNAcα1-O-Ser/Thr) antigens are examples of tumor-associated antigens. Increased expression of Tn- and T-antigens is associated with tumor invasion and metastasis, and patients with high concentration of anti-Tn and...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zlocowski, Natacha, Grupe, Veronica, Garay, Yohana C., Nores, Gustavo A., Lardone, Ricardo D., Irazoqui, Fernando J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6543037/
https://ncbi.nlm.nih.gov/pubmed/31147593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44601-9
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