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Investigation of factors influencing the separation of diastereomers of phosphorothioated oligonucleotides
This study presents a systematic investigation of factors influencing the chromatographic separation of diastereomers of phosphorothioated pentameric oligonucleotides as model solutes. Separation was carried out under ion-pairing conditions using an XBridge C(18) column. For oligonucleotides with a...
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| Veröffentlicht in: | Anal Bioanal Chem |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer Berlin Heidelberg
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6543027/ https://ncbi.nlm.nih.gov/pubmed/31020370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-019-01813-2 |
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