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Ring Opening of Epoxides with [(18)F]FeF Species to Produce [(18)F]Fluorohydrin PET Imaging Agents
A simple technique for the preparation of [(18)F]HF has been developed and applied to the generation of an [(18)F]FeF species for opening sterically hindered epoxides. This method has been successfully employed to prepare four drug-like molecules, including 5-[(18)F]fluoro-6-hydroxy-cholesterol, a p...
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| 發表在: | Chem Commun (Camb) |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6542722/ https://ncbi.nlm.nih.gov/pubmed/31062010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9cc02779c |
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