Sensory Experience Remodels Genome Architecture in Neural Circuit to Drive Motor Learning

Neuronal activity-dependent transcription couples sensory experience to adaptive responses of the brain including learning and memory. Mechanisms of activity-dependent gene expression including alterations of the epigenome have been characterized(1–8). However, the fundamental question of whether an...

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Pubblicato in:Nature
Autori principali: Yamada, Tomoko, Yang, Yue, Valnegri, Pamela, Juric, Ivan, Abnousi, Armen, Markwalter, Kelly H., Guthrie, Arden N., Godec, Abigail, Oldenborg, Anna, Hu, Ming, Holy, Timothy E., Bonni, Azad
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542709/
https://ncbi.nlm.nih.gov/pubmed/31068695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1190-7
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