Alteration of myocardial GRK2 produces a global metabolic phenotype

A vast body of literature has established G protein–coupled receptor kinase 2 (GRK2; family: β-adrenergic receptor kinases [βARKs]) as a key player in the development and progression of heart failure. Inhibition of GRK2 improves cardiac function after injury in numerous animal models. In recent year...

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Bibliographic Details
Published in:JCI Insight
Main Authors: Woodall, Benjamin P., Gresham, Kenneth S., Woodall, Meryl A., Valenti, Mesele-Christina, Cannavo, Alessandro, Pfleger, Jessica, Chuprun, J. Kurt, Drosatos, Konstantinos, Koch, Walter J.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2019
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542603/
https://ncbi.nlm.nih.gov/pubmed/30946029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.123848
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