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Ventral hippocampal projections to the medial prefrontal cortex regulate social memory

Inputs from the ventral hippocampus (vHIP) to the medial prefrontal cortex (mPFC) are implicated in several neuropsychiatric disorders. Here, we show that the vHIP-mPFC projection is hyperactive in the Mecp2 knockout mouse model of the autism spectrum disorder Rett syndrome, which has deficits in so...

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Pubblicato in:eLife
Autori principali: Phillips, Mary L, Robinson, Holly Anne, Pozzo-Miller, Lucas
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542587/
https://ncbi.nlm.nih.gov/pubmed/31112129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44182
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