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Ventral hippocampal projections to the medial prefrontal cortex regulate social memory

Inputs from the ventral hippocampus (vHIP) to the medial prefrontal cortex (mPFC) are implicated in several neuropsychiatric disorders. Here, we show that the vHIP-mPFC projection is hyperactive in the Mecp2 knockout mouse model of the autism spectrum disorder Rett syndrome, which has deficits in so...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Phillips, Mary L, Robinson, Holly Anne, Pozzo-Miller, Lucas
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542587/
https://ncbi.nlm.nih.gov/pubmed/31112129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44182
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