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Ventral hippocampal projections to the medial prefrontal cortex regulate social memory

Inputs from the ventral hippocampus (vHIP) to the medial prefrontal cortex (mPFC) are implicated in several neuropsychiatric disorders. Here, we show that the vHIP-mPFC projection is hyperactive in the Mecp2 knockout mouse model of the autism spectrum disorder Rett syndrome, which has deficits in so...

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Foilsithe in:eLife
Main Authors: Phillips, Mary L, Robinson, Holly Anne, Pozzo-Miller, Lucas
Formáid: Artigo
Teanga:Inglês
Foilsithe: eLife Sciences Publications, Ltd 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542587/
https://ncbi.nlm.nih.gov/pubmed/31112129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44182
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