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Implications of Pyran Cyclization and Pterin Conformation on Oxidized Forms of the Molybdenum Cofactor

The large family of mononuclear molybdenum and tungsten enzymes all possess the special ligand molybdopterin (MPT), which consists of a metal-binding dithiolene chelate covalently bound to a pyranopterin group. MPT pyran cyclization/scission processes have been proposed to modulate the reactivity of...

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Publicat a:J Am Chem Soc
Autors principals: Gisewhite, Douglas R., Yang, Jing, Williams, Benjamin R., Esmail, Alisha, Stein, Benjamin, Kirk, Martin L., Burgmayer, Sharon J. N.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542470/
https://ncbi.nlm.nih.gov/pubmed/30200760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b05777
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