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Integrative Data Mining, Scaffold Analysis, and Sequential Binary Classification Models for Exploring Ligand Profiles of Hepatic Organic Anion Transporting Polypeptides

[Image: see text] Hepatocellular organic anion transporting polypeptides (OATP1B1, OATP1B3, and OATP2B1) are important for proper liver function and the regulation of the drug elimination process. Understanding their roles in different conditions of liver toxicity and cancer requires an in-depth inv...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Chem Inf Model
Prif Awduron: Türková, Alžběta, Jain, Sankalp, Zdrazil, Barbara
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2018
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541895/
https://ncbi.nlm.nih.gov/pubmed/30372058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.8b00466
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