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Integrative Data Mining, Scaffold Analysis, and Sequential Binary Classification Models for Exploring Ligand Profiles of Hepatic Organic Anion Transporting Polypeptides

[Image: see text] Hepatocellular organic anion transporting polypeptides (OATP1B1, OATP1B3, and OATP2B1) are important for proper liver function and the regulation of the drug elimination process. Understanding their roles in different conditions of liver toxicity and cancer requires an in-depth inv...

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Pubblicato in:J Chem Inf Model
Autori principali: Türková, Alžběta, Jain, Sankalp, Zdrazil, Barbara
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2018
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541895/
https://ncbi.nlm.nih.gov/pubmed/30372058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.8b00466
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