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Runx2 stimulates neoangiogenesis through the Runt domain in melanoma

Runx2 is a transcription factor involved in melanoma cell migration and proliferation. Here, we extended the analysis of Runt domain of Runx2 in melanoma cells to deepen understanding of the underlying mechanisms. By the CRISPR/Cas9 system we generated the Runt KO melanoma cells 3G8. Interestingly,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cecconi, Daniela, Brandi, Jessica, Manfredi, Marcello, Serena, Michela, Carbonare, Luca Dalle, Deiana, Michela, Cheri, Samuele, Parolini, Francesca, Gandini, Alberto, Marchetto, Giulia, Innamorati, Giulio, Avanzi, Francesco, Antoniazzi, Franco, Marengo, Emilio, Tiso, Natascia, Mottes, Monica, Zipeto, Donato, Valenti, Maria Teresa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541657/
https://ncbi.nlm.nih.gov/pubmed/31142788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44552-1
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