A Potential Role of RUNX2- RUNT Domain in Modulating the Expression of Genes Involved in Bone Metastases: An In Vitro Study with Melanoma Cells

Ectopic expression of RUNX2 has been reported in several tumors. In melanoma cells, the RUNT domain of RUNX2 increases cell proliferation and migration. Due to the strong link between RUNX2 and skeletal development, we hypothesized that the RUNT domain may be involved in the modulation of mechanisms...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cells
Autori principali: Deiana, Michela, Dalle Carbonare, Luca, Serena, Michela, Cheri, Samuele, Mutascio, Simona, Gandini, Alberto, Innamorati, Giulio, Lorenzi, Pamela, Cumerlato, Michela, Bertacco, Jessica, Antoniazzi, Franco, Romanelli, Maria Grazia, Mottes, Monica, Zipeto, Donato, Valenti, Maria Teresa
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140624/
https://ncbi.nlm.nih.gov/pubmed/32204402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9030751
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi