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Ep400 deficiency in Schwann cells causes persistent expression of early developmental regulators and peripheral neuropathy

Schwann cells ensure efficient nerve impulse conduction in the peripheral nervous system. Their development is accompanied by defined chromatin changes, including variant histone deposition and redistribution. To study the importance of variant histones for Schwann cell development, we altered their...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Fröb, Franziska, Sock, Elisabeth, Tamm, Ernst. R., Saur, Anna-Lena, Hillgärtner, Simone, Williams, Trevor J., Fujii, Toshihiro, Fukunaga, Rikiro, Wegner, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541636/
https://ncbi.nlm.nih.gov/pubmed/31142747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10287-w
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