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REDD1 Activates a ROS-Generating Feedback Loop in the Retina of Diabetic Mice

PURPOSE: The present study was designed to evaluate the role of the stress response protein REDD1 in diabetes-induced oxidative stress and retinal pathology. METHODS: Wild-type and REDD1-deficient mice were administered streptozotocin to induce diabetes. Some mice received the antioxidant N-acetyl-l...

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Bibliographische Detailangaben
Veröffentlicht in:Invest Ophthalmol Vis Sci
Hauptverfasser: Miller, William P., Toro, Allyson L., Barber, Alistair J., Dennis, Michael D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Association for Research in Vision and Ophthalmology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541429/
https://ncbi.nlm.nih.gov/pubmed/31141608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.19-26606
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