Φορτώνει......
Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis
The HIF family of hypoxia-inducible transcription factors are key mediators of the physiologic response to hypoxia, whose dysregulation promotes tumorigenesis. One important HIF-1 effector is the REDD1 protein, which is induced by HIF-1 and which functions as an essential regulator of TOR complex 1...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
National Academy of Sciences
2010
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2842042/ https://ncbi.nlm.nih.gov/pubmed/20176937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907705107 |
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