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Unexpected polymorphism during a catalyzed mechanochemical Knoevenagel condensation

The transformation of a base-catalyzed, mechano-assisted Knoevenagel condensation of mono-fluorinated benzaldehyde derivatives (p-, m-, o-benzaldehyde) with malonodinitrile was investigated in situ and in real time. Upon milling, the para-substituted product was found to crystallize initially into t...

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Bibliografiske detaljer
Udgivet i:Beilstein J Org Chem
Main Authors: Haferkamp, Sebastian, Paul, Andrea, Michalchuk, Adam A L, Emmerling, Franziska
Format: Artigo
Sprog:Inglês
Udgivet: Beilstein-Institut 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541349/
https://ncbi.nlm.nih.gov/pubmed/31164950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.15.110
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