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Reversible and Tunable Photoswitching of Protein Function through Genetic Encoding of Azobenzene Amino Acids in Mammalian Cells
The genetic encoding of three different azobenzene phenylalanines with different photochemical properties was achieved in human cells using an engineered pyrrolysyl tRNA/tRNA synthetase pair. In order to demonstrate reversible light-control of protein function, azobenzenes were site-specifically int...
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| Udgivet i: | Chembiochem |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6540996/ https://ncbi.nlm.nih.gov/pubmed/30277634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201800226 |
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