The Role of 5-ALA in Low-Grade Gliomas and the Influence of Antiepileptic Drugs on Intraoperative Fluorescence

Objectives: Intraoperative tumor visualization with 5-aminolevulinic acid (5-ALA) induced protoporphyrin IX (PpIX) fluorescence is widely applied for improved resection of high-grade gliomas. However, visible fluorescence is present only in a minority of low-grade gliomas (LGGs) according to current...

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Dettagli Bibliografici
Pubblicato in:Front Oncol
Autori principali: Goryaynov, Sergey A., Widhalm, Georg, Goldberg, Maria F., Chelushkin, Danil, Spallone, Aldo, Chernyshov, Kosta A., Ryzhova, Marina, Pavlova, Galina, Revischin, Alexander, Shishkina, Ludmila, Jukov, Vadim, Savelieva, Tatyana, Victor, Loschenov, Potapov, Alexander
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Oncology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540822/
https://ncbi.nlm.nih.gov/pubmed/31192128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00423
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