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The Role of 5-ALA in Low-Grade Gliomas and the Influence of Antiepileptic Drugs on Intraoperative Fluorescence

Objectives: Intraoperative tumor visualization with 5-aminolevulinic acid (5-ALA) induced protoporphyrin IX (PpIX) fluorescence is widely applied for improved resection of high-grade gliomas. However, visible fluorescence is present only in a minority of low-grade gliomas (LGGs) according to current...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Goryaynov, Sergey A., Widhalm, Georg, Goldberg, Maria F., Chelushkin, Danil, Spallone, Aldo, Chernyshov, Kosta A., Ryzhova, Marina, Pavlova, Galina, Revischin, Alexander, Shishkina, Ludmila, Jukov, Vadim, Savelieva, Tatyana, Victor, Loschenov, Potapov, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540822/
https://ncbi.nlm.nih.gov/pubmed/31192128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00423
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