Myeloid Cell mPges-1 Deletion Attenuates Mortality Without Affecting Remodeling After Acute Myocardial Infarction in Mice

Selective deletion of microsomal prostaglandin E(2) synthase-1 (mPges-1) in myeloid cells retards atherogenesis and suppresses the vascular proliferative response to injury, while it does not predispose to thrombogenesis or hypertension. However, studies using bone marrow transplants from irradiated...

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Bibliografske podrobnosti
izdano v:J Pharmacol Exp Ther
Main Authors: Chen, Lihong, Yang, Guangrui, Jiang, Tingting, Tang, Soon Yew, Wang, Tao, Wan, Qing, Wang, Miao, FitzGerald, Garret A.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2019
Teme:
Cardiovascular
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540703/
https://ncbi.nlm.nih.gov/pubmed/30992314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.118.256057
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