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mPGES-1 deletion impairs diuretic response to acute water loading

PGE(2) has an established role in renal water handling. The present study was undertaken to examine the role of microsomal prostaglandin E synthase-1 (mPGES-1) in the diuretic response to acute and chronic water loading. Compared with wild-type (+/+) controls, mPGES-1 −/− mice exhibited impaired abi...

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Detalhes bibliográficos
Main Authors: Soodvilai, Sunhapas, Jia, Zhanjun, Wang, Mong-Heng, Dong, Zheng, Yang, Tianxin
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681360/
https://ncbi.nlm.nih.gov/pubmed/19225050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90478.2008
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