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mPGES-1 deletion potentiates urine concentrating capability after water deprivation

PGE(2) plays an important role in the regulation of fluid metabolism chiefly via antagonizing vasopressin-induced osmotic permeability in the distal nephron, but its enzymatic sources remain uncertain. The present study was undertaken to investigate the potential role of microsomal PGE synthase (mPG...

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Detalhes bibliográficos
Main Authors: Jia, Zhanjun, Liu, Gang, Downton, Maicy, Dong, Zheng, Zhang, Aihua, Yang, Tianxin
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330718/
https://ncbi.nlm.nih.gov/pubmed/22237797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00508.2011
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