This is a platform alteration: a trial management perspective on the operational aspects of adaptive and platform and umbrella protocols

BACKGROUND: There are limited research and literature on the trial management challenges encountered in running adaptive platform trials. This trial design allows both (1) the seamless addition of new research comparisons when compelling clinical and scientific research questions emerge, and (2) ear...

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Detalhes bibliográficos
Publicado no:Trials
Main Authors: Schiavone, Francesca, Bathia, Riya, Letchemanan, Krishna, Masters, Lindsey, Amos, Claire, Bara, Anna, Brown, Louise, Gilson, Clare, Pugh, Cheryl, Atako, Nafisah, Hudson, Fleur, Parmar, Mahesh, Langley, Ruth, Kaplan, Richard S., Parker, Chris, Attard, Gert, Clarke, Noel W., Gillessen, Silke, James, Nicholas D., Maughan, Tim, Sydes, Matthew R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Methodology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540525/
https://ncbi.nlm.nih.gov/pubmed/31138317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-019-3216-8
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