Changing platforms without stopping the train: experiences of data management and data management systems when adapting platform protocols by adding and closing comparisons

BACKGROUND: There is limited research and literature on the data management challenges encountered in multi-arm, multi-stage platform and umbrella protocols. These trial designs allow both (1) seamless addition of new research comparisons and (2) early stopping of accrual to individual comparisons t...

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Detalhes bibliográficos
Publicado no:Trials
Main Authors: Hague, Dominic, Townsend, Stephen, Masters, Lindsey, Rauchenberger, Mary, Van Looy, Nadine, Diaz-Montana, Carlos, Gannon, Melissa, James, Nicholas, Maughan, Tim, Parmar, Mahesh K. B., Brown, Louise, Sydes, Matthew R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Methodology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540437/
https://ncbi.nlm.nih.gov/pubmed/31138292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-019-3322-7
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