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Effects of MUL1 and PARKIN on the circadian clock, brain and behaviour in Drosophila Parkinson’s disease models

BACKGROUND: Mutants which carry mutations in genes encoding mitochondrial ligases MUL1 and PARKIN are convenient Drosophila models of Parkinson’s disease (PD). In several studies it has been shown that in Parkinson’s disease sleep disturbance occurs, which may be the result of a disturbed circadian...

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Detalhes bibliográficos
Publicado no:BMC Neurosci
Main Authors: Doktór, Bartosz, Damulewicz, Milena, Pyza, Elżbieta
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540415/
https://ncbi.nlm.nih.gov/pubmed/31138137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-019-0506-8
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