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Effects of MUL1 and PARKIN on the circadian clock, brain and behaviour in Drosophila Parkinson’s disease models
Abstract Background Mutants which carry mutations in genes encoding mitochondrial ligases MUL1 and PARKIN are convenient Drosophila models of Parkinson’s disease (PD). In several studies it has been shown that in Parkinson’s disease sleep disturbance occurs, which may be the result of a disturbed ci...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BMC
2019-05-01
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Colecção: | BMC Neuroscience |
Assuntos: | |
Acesso em linha: | http://link.springer.com/article/10.1186/s12868-019-0506-8 |
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