Novel sporozoite-based ELISpot assay to assess frequency of parasite-specific B cells after vaccination with irradiated sporozoites

BACKGROUND: Whole parasite vaccination is an efficacious strategy to induce sterile immunity and to prevent malaria transmission. Understanding the mechanism and response of immune cells to vaccines plays a critical role in deciphering correlates of protection against infection and disease. Immunoas...

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Bibliografische gegevens
Gepubliceerd in:Malar J
Hoofdauteurs: Atre, Tanmaya, Robinson, Tanisha M., Savransky, Tatyana, Dutta, Sheetij, Epstein, Judith E., Bergmann-Leitner, Elke S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2019
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Methodology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540377/
https://ncbi.nlm.nih.gov/pubmed/31142328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-019-2819-6
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