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Formulation of Nanomicelles to Improve the Solubility and the Oral Absorption of Silymarin

Two novel nanomicellar formulations were developed to improve the poor aqueous solubility and the oral absorption of silymarin. Polymeric nanomicelles made of Soluplus and mixed nanomicelles combining Soluplus with d-α-tocopherol polyethylene glycol 1000 succinate (vitamin E TPGS) were prepared usin...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Piazzini, Vieri, D’Ambrosio, Mario, Luceri, Cristina, Cinci, Lorenzo, Landucci, Elisa, Bilia, Anna Rita, Bergonzi, Maria Camilla
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540123/
https://ncbi.nlm.nih.gov/pubmed/31052197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24091688
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